Disease: Anaplastic astrocytoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
SETD2 Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 1.00 0.424 0.846
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
OLIG2 Q13516 oligodendrocyte transcription factor 2 Enzyme 9.5E-02 0.560 0.577
NOTCH2 Q04721 notch receptor 2 1.00 0.441 0.808
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
NDRG1 Q92597 N-myc downstream regulated 1 Enzyme 1.1E-02 0.488 0.731
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846
MDM4 O15151 MDM4 regulator of p53 Nucleic acid binding 1.00 0.461 0.808
LOC110806263 TERT 5' regulatory region 0.464 0.731
IDH2 P48735 isocitrate dehydrogenase (NADP(+)) 2 0.88 0.434 0.808
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
HEY1 Q9Y5J3 hes related family bHLH transcription factor with YRPW motif 1 Transcription factor 5.0E-02 0.551 0.692
H3-3A P84243 H3.3 histone A 0.12 0.559 0.692
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962